DMSO Myth-Busting Series: Part 4 – Pregnancy and Breastfeeding
DMSO Myth-Busting Series: Part 4 – Pregnancy and Breastfeeding
DMSO During Pregnancy and Breastfeeding: Video Overview
In Part 4 of her DMSO Myth-Busting Series, Amandha Vollmer (ADV) addresses DMSO during pregnancy and breastfeeding and begins with an important point: these are situations where she believes additional caution is appropriate. ADV discusses the limited human data available, then explains why she looks closely at the route, dose and method used when interpreting DMSO research. She reviews animal studies involving oral, topical and injected DMSO and explains how she interprets the different outcomes reported with these routes.
The discussion then moves to breastfeeding. ADV reviews a study involving one nursing mother who received a 50% DMSO solution intravesically for interstitial cystitis. She discusses the amount subsequently measured in breast milk, while also acknowledging that the child’s health was not followed and that more research is needed in breastfeeding women.
ADV closes by explaining why she considers DMSO’s carrier properties, medications, alcohol and the mother’s overall health when thinking through use during pregnancy or breastfeeding. She shares the low-dose topical approach she has recommended in her own practice and advises working with a knowledgeable practitioner when considering more intensive applications.
What You’ll Learn About DMSO During Pregnancy and Breastfeeding
- Why ADV recommends approaching DMSO more cautiously during pregnancy and breastfeeding
- How route, concentration and dose influence the way she interprets DMSO safety studies
- What animal studies discussed in the video report about oral and topical DMSO during pregnancy
- Why ADV distinguishes those studies from high-dose injected DMSO research
- What the single breastfeeding study discussed in the video measured in human milk
- Why ADV says more breastfeeding-specific DMSO research is still needed
- How DMSO’s carrier properties, medications and alcohol enter her assessment
- The low-dose topical approach ADV describes from her own experience with pregnant and breastfeeding mothers
Important Context & Safety
Educational context: This video presents Amandha Vollmer’s interpretation of animal research, one human lactation study and her own experience discussing DMSO with pregnant and breastfeeding women. Current U.S. prescribing information states that there are no adequate and well-controlled DMSO studies in pregnant women. It reports different findings across animal studies, including teratogenic effects with high-dose intraperitoneal administration and differing results with topical exposure. The label states that DMSO should be used during pregnancy only when the potential benefit justifies the potential risk to the fetus.
For breastfeeding, LactMed reports that human-milk DMSO levels have been measured in only one patient after a 50 mL, 50% intravesical treatment. The relative infant dose was estimated at 0.45%. LactMed also notes that this single intravesical case cannot be used to estimate infant exposure after maternal oral use because systemic absorption differs by route, the DMSO metabolite was not measured, and published information about effects in breastfed infants is not available.
Medical emergencies: Information in this video should not be used to delay emergency assessment or treatment for symptoms of stroke, heart attack, serious head injury or another medical emergency.
Full Video Transcript
Transcript note: This transcript has been lightly edited for punctuation, spelling and readability while preserving the speakers’ meaning and conversational format.
Introduction: DMSO in Pregnancy and Breastfeeding
Amandha: Welcome to part four of my DMSO myth-busting series, and today’s topic is going to be DMSO in pregnancy and breastfeeding. Let me just say, this is not medical advice, and always see your practitioner before starting any medication or supplement regimen. First, I should say, when it comes to pregnancy and breastfeeding, across the board, we generally proceed with caution.
Amandha: There are limited data sets and studies done on pregnant and lactating women when it comes to holistic medicine. We could extrapolate as to why that is. However, there have been a lot of studies on DMSO when it comes to cryopreservation of fetuses and when it comes to injection studies on animals. As I mentioned in previous videos, we have a lot of studies that use methods that really don’t pertain to us.
Pregnancy Studies: Route, Dose, and Animal Research
Amandha: So, when we’re describing toxicity, we need to consider the mode and method of how it’s being used and applied or ingested. Keeping in mind that one teaspoon of DMSO is five millilitres, there have been plenty of studies that have used topical and oral doses in animals like rabbits, rats, and guinea pigs that showed zero toxicity levels whatsoever in those studies.
Amandha: For example, there was a study in rabbits where they were given 27.3 millilitres in total. It was diluted, but if you added it up in total into those rabbits by oral use, they were pregnant and developed zero issues with fetal weight. The mothers were eating properly.
Amandha: There were no negative side effects that they could find in that study. Allow me to read from my notes. Oral DMSO was given to pregnant rabbits. They received five millilitres per kilogram. That was oral administration in gestating rabbits, and there were no significant pregnancy losses. The fetal weight was stable, and there were no malformations.
Amandha: Oral DMSO did not cause any reproductive problems in rats, mice, or hamsters at the dosage that they studied, which was similar to the previous study. When it comes to topical application of DMSO, the studies are even more positive. Pregnant rabbits received 1.1 millilitres per kilogram per day from gestation day three through sixteen.
Amandha: That’s one millilitre of pure DMSO per kilogram per day. No fetal abnormalities were found. The studies have shown that injecting DMSO in high doses in animals did produce issues in fertility and other concerns, which we are not doing when we are applying it topically or using it internally, and we’re not pushing it to extreme dosages. I believe it because I know what’s going on.
Breastfeeding Study and Human Milk Exposure
Amandha: We only have one breastfeeding study. I know every woman listening to this is just shocked. But we have one, and it’s a woman who must have had interstitial cystitis because she was given the FDA-approved DMSO injection for that and was given 50 millilitres of a 50% DMSO solution intravesically, which is right into the bladder directly.
Amandha: They retained that for 15 minutes and then evacuated. The highest level of DMSO that was found in the breast milk was about five hours later, and it was 34.5 milligrams or millilitres per litre. That means the average concentration was only 13.4 millilitres per litre because it was a 50%, and the relative infant dose of the breast milk would have been 0.45%, which is extremely low.
Amandha: Which tells us that the body is filtering out the DMSO and the breast milk is not carrying very much of the dosage that is given, and that was a very high dose. They did not follow up with the health and welfare of the child. So I would say we need more studies on this topic, and that’s what’s kind of disappointing when you’re fighting against an industry that really doesn’t want you to know how to use something and how to research it, or to even have research studies on it.
Amandha: I also want to remind you, which I also mentioned in my book, that everyone has been exposed to DMSO whether you know it or not because it’s in many foods and it is also coming right out of the ocean. Phytoplankton make DMSO and also consume DMSO in quite high levels, and you are exposed to it just walking seaside in the air.
Amandha: The other is that a lot of grains and vegetables and herbs and things, anything that has a sort of turgid structure, contains dimethyl sulfoxide, and if you’ve eaten a food then you’ve had DMSO in your system before. Like I said, this is a natural substance found in nature, found in trees, found in plants, found in the ocean, found in life forms, and there is no evidence that there is any danger in low doses taking and using DMSO orally or topically when pregnant or breastfeeding.
Caution, Carrier Effects, and ADV's Practical Guidance
Amandha: Now, we still are going to apply caution, and why we want to do that is not just because of the DMSO itself. As we know, as I’ve been teaching you, DMSO has special qualities carrying other nutrients and so forth into tissues, helping the blood flow and get extra delivery of those nutrients, and even if there’s drugs in the system or alcohol in the system.
Amandha: Therefore, the issues that we face when it comes to DMSO and pregnancy and breastfeeding really pertain to the health of the mother. When the body is clean, when the mother has prepared for birth properly, ideally up to a year before pregnancy, and avoids toxicity as much as possible, then we know that those levels are low and the likelihood of anything, even in low doses, getting into fetal tissue or in breast tissue is extremely negligible.
Amandha: In my own field research, if you will, I’ve had lots of mothers ask me this question over the last 10 years. What I routinely tell them is it depends on you, and I suggest one product usage per day. For example, my Face Lift in a Jar, which is very well loved and a lot of people don’t want to give that one up, is a 25% DMSO cream for wrinkles, and it actually does tonify and tighten up the skin.
Amandha: That can be used while pregnant or breastfeeding once a day on clean facial skin and the neck and chest area. If you are treating something, you can safely use my 50% DMSO with magnesium on clean skin, about five sprays once or twice a day. These are very low numbers. We’ve seen zero scientific studies that have shown any harm or any danger whatsoever, and if you are clean in your diet and lifestyle, there’s no issue using low doses whatsoever. If you’re going into deeper treatments, then it would be best to work with a knowledgeable health practitioner if you need to go to higher doses.
Amandha: See you in the next one.
Related DMSO Videos & Resources
DMSO Myth Busting Series – Part 2: DMSO Toxicity: https://yummy.doctor/video-list/dmso-myth-busting-series-part-2-dmso-toxicity/
Learning About DMSO: A Beginner Class with Amandha Vollmer (ADV): https://yummy.doctor/video-list/learning-about-dmso-a-beginner-class-with-amandha-vollmer-adv/
What to Know About Internal DMSO Use: https://yummy.doctor/video-list/what-to-know-about-internal-dmso-use/
DMSO: More Natural Than You Think: https://yummy.doctor/video-list/dmso-more-natural-than-you-think/
FREE Webinar: DMSO Decoded – 45 Myths Busted With Facts and Clinical Experience: https://yummy.doctor/video-list/dmso-decoded-45-myths-busted-with-facts-and-clinical-experience/
Healing with DMSO (Dimethyl Sulfoxide) Book: https://healingwithdmso.com/
Dimethyl Sulfoxide – DMSO Store: https://dmso.store/
Related Links
Yum Naturals: https://yumnaturals.store/
Publication/Update Information
Originally published August 25, 2026
Transcript and educational resources updated August 2026
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Amandha D Vollmer
BSc, Herbalist, Reiki Master,
Holistic Health Practitioner,
Degree of Doctor of Naturopathic Medicine
About Amandha Vollmer (ADV):
Amandha Vollmer (ADV) is the author of Healing with DMSO and a holistic health educator whose work explores natural health, DMSO, self-care and health sovereignty.
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Bringing the Wisdom of Nature Education: https://yummy.doctor/
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Healing with DMSO Book: https://healingwithdmso.com/
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